MPRIP and infection: We therefore hypothesized that the primary infection with mAdV2, through upregulation of Mprip causes actin remodeling, allowing for the increased uptake of Yersinia. To test this, we depleted Mprip-levels by siRNA knockdown, using a pool of four siRNAs targeting Mprip (Figure S6E), and subsequently assessed the uptake of Yersinia by the host cells via FC.