After deletion of PCBP2 phosphorylation, this affinity is also reduced, which promotes C/EBPα expression efficiency and G-CSFR-driven neutrophil maturation, initiating differentiation of chronic myeloid leukemia blastoblastic crisis (CML-BC) progenitor cells [91]. This evidence concerns the gene PCBP2 and chronic myelogenous leukemia, BCR-ABL1 positive.