Among women with PCOS, we found that more MVPA relative to other behaviours was significantly associated with lower waist circumference, triglyceride, fs-insulin, and HOMA-IR values, while among the controls, in addition to these cardiometabolic markers, we observed beneficial associations with fp-glucose, 2-h glucose, 2-h insulin, hs-CRP, and MAP. The gene discussed is INS; the disease is polycystic ovary syndrome.