In research using neuronal networks derived from hiPSCs of patients with Dravet syndrome (DS), generalized epilepsy with febrile seizures plus (GEFS+), and febrile seizures with mutations in SCN1A, fragmented NBs were the main phenotypic driver (Van Hugte et al., 2023). The gene discussed is SCN1A; the disease is Febrile seizure (within the age range of 3 months to 6 years).