Peripheral blood eosinophilia (2200/μL), 95% polymorphonuclear eosinophils in ascitic fluid, elevated total serum IgE (>390 kU/L), eosinophilic infiltration in the lamina propria of the duodenum (40 eosinophils/hpf). The gene discussed is IGHE; the disease is Increased total eosinophil count.