Multivariate logistic regression identified hypertension (OR = 13.95%, 95% CI: 4.52, 50.07%), blood urea nitrogen (BUN) (OR = 1.57, 95% CI: 1.06–2.40), cystatin C (CyC) (OR = 4.90, 95% CI: 1.20–22.16), and urinary β-2 microglobulin, (OR = 2.11, 95% CI: 1.45–3.49) as significant risk factors for CMBs. This evidence concerns the gene CST3 and hypertensive disorder.