In addition, the dual stainings of Annexin V+ LEVs, Annexin V+ PEVs, Annexin V+ REVs, and Annexin V+ EEVs were also elevated in both SLE patient groups as comparted to those in HC subjects (Figures 2F–I), indicating the increased generation of EVs from leukocytes, platelets, RBCs, and vascular endothelium in SLE patients no matter if they have PAH or not. This evidence concerns the gene ANXA5 and systemic lupus erythematosus.