A unifying feature of all the genetic subtypes of MM is the ectopic expression of a cyclin D gene because of chromosome translocation, direct transactivation of CCND2 by a MAF family gene, or indirect transactivation of a low level of CCND1 and/or CCND2 by unknown mechanisms (Bergsagel et al. 2005). Here, CCND2 is linked to Miyoshi myopathy.