PSMA PET/CT scan demonstrated abnormal tracer activity in the posterior prostatic peripheral zone at the mid-gland and prostatic base, with the highest uptake intensity noted at the left posterolateral prostatic mid-gland peripheral zone. Additionally, there was focal intense tracer activity in the spleen consistent with metastatic prostate cancer based on tracer avidity and specificity for PSMA expression on prostate cancer cells (Figures 3, 4). This evidence concerns the gene FOLH1 and metastatic prostate carcinoma.