Numerous secondary metabolites inhibit the growth of cancer by targeting NF-kB (nuclear factor kappa B) and AP1 (activator protein 1), blocking PKC (protein kinase C) and c-JUN NH2-terminal kinase (JNK), stopping the expression of AKT (protein kinase B), and preventing activation of PI3K (Ugbogu et al., 2013). The gene discussed is AKT1; the disease is cancer.