C4B and tuberculosis: In addition to cxcl9 and camp, the significantly upregulated DE genes in the TB model group vs. normal group also included cfb (Shi et al., 2022), c4b (Daher et al., 2015; Wang et al., 2023), and ngp (Kathamuthu et al., 2021), which are closely related to the host’s anti-TB immune function.