Many studies have reported that age was not associated with EGFR mutations (Gao et al., 2020; Zhao et al., 2018; Yang et al., 2014), while some investigators found EGFR mutations were more frequent in younger or older patients with NSCLC (Vallee et al., 2013; Wu et al., 2019). This evidence concerns the gene EGFR and non-small cell lung carcinoma.