PIK3CA and non-small cell lung carcinoma: In this retrospective study, participants were recruited to undergo the detection of 10 target oncogene aberrations, including EGFR, KRAS, MET, ALK, ROS1, HER2, RET, BRAF, NRAS, and PIK3CA. The chi-squared test, Fisher exact test, and logistic regression analysis were used to analyze the relationship between 10 driver gene alterations and the clinicopathological characteristics of NSCLC patients.