Furthermore, through three logistics regression models, we found that the probability of EGFR mutations was positively correlated with women, non-smokers, lung adenocarcinoma, and IA subtype of adenocarcinoma, while EGFR mutations were negatively correlated with solid nodule, the MIA subtype of adenocarcinoma, and the solid-predominant adenocarcinoma subtype of IA. This evidence concerns the gene EGFR and adenocarcinoma.