The molecular landscape of mucosal melanoma is characterized by a low point mutation burden, with high numbers of copy number and structural variants and mutations in mitogen-activated protein kinase (MAPK) pathway genes such as NRAS, BRAF, NF1, and KIT, as well as SF3B1, TP53, SPRED1, ATRX, HLA-A, CDH8, and CTNNB1. This evidence concerns the gene KIT and melanoma.