MLANA and melanoma: Immunohistochemical studies showed diffusely positive SOX10 (Figure 3A), Melan-A (Figure 3B), HMB-45 (Figure 3C), preferentially expressed antigen in melanoma (PRAME) (Figure 3D) and patchy S100 (Figure 3E) immunoreactivity and were negative for p63 (Figure 3F) and GATA3, supporting the diagnosis of melanoma.