Among upregulated genes in PDOs derived from basal-like tumors were genes that have been associated with tumor progression or cell survival including BAG3 [42] (log-rank p = 0.0015), DUSP14 [43] (log-rank p = 0.014), and LYPD3 [44] (log-rank p = 0.013). The gene discussed is LYPD3; the disease is neoplasm.