HES1 and glioblastoma: While both were enriched in vascular cells (C30), the hypoxia-independent subgroup was enriched in astrocytes (C2, C27), and the hypoxia-dependent subgroup was enriched in radial glial subtypes expressing HES1 (C4, C18), implying a possible resemblance of each astrocyte and radial glial subtype to mesenchymal-like glioblastoma.