TLX2 and heart failure: Our study also reveals that in contrast to pressure-overload-induced heart failure (HF) and dilated cardiomyopathy where expression of sodium-calcium exchanger (NCX) and calmodulin-dependent protein kinase II delta (CaMKIIδ) are typically upregulated, cardiomyopathy in FA was associated with decreased expression in NCX and CaMKIIδ in both males and females.