In addition, there was a 38% decrease in circulating levels of the follicle-stimulating hormone (FSH, from 6.11 ± 4.13 in healthy males to 3.82 ± 3.06 mIU/ml in individuals with SCA2) and ~16% decrease in luteinizing hormone (LH) levels (from 4.36 ± 1.92 in healthy males to 3.65 ± 2.86 mIU/ml in SCA2 affected males). This evidence concerns the gene BRD2 and spinocerebellar ataxia type 2.