Immunohistochemistry of untreated and TP-treated tumors showed Ki-67, P21, P16, uPAR, and β-gal staining in sequential slides (Supplemental Fig. 9), revealing heterogeneity in each tumor—particularly uPAR and β-gal staining as adjacent stains—and uPAR staining closely matching Ki-67 staining patterns. Here, MKI67 is linked to neoplasm.