SNAI1 and familial pancreatic carcinoma: Further, Snail has been associated with aggressive phenotypes such as chemoresistance in human pancreatic cancer (Zheng et al., 2015), but not with the mesenchymal trait in human breast cancer cells and human HNSCC cells (Fukagawa et al., 2015; Horiguchi et al., 2012; Sakamoto et al., 2021).