INS and gestational diabetes: In a retrospective cohort study that compared the perinatal outcomes of women with GDM in Belgium, insulin treatment did not prevent adverse events such as the rates of large-for-gestational-age newborns and these women have a higher risk profile, impaired beta-cell function and lower insulin sensitivity,4 but it is not yet known whether, even when treated with insulin therapy and lifestyle changes (diet and physical activity), there is a greater impact on perinatal outcomes, such as hospitalization, birth complications, and breastfeeding.