APOE and dementia: Risk factors for dementia, the most common type of ND, include older age, genetic risk factors (family history of dementia and Apolipoprotein E), cardiometabolic risk factors (diabetes mellitus, hypertension, dyslipidemia, obesity, and vascular disease), smoking, hearing impairment, depression, less education, physical inactivity, alcohol consumption, traumatic brain injury, and air pollution [2-7].