Furthermore, the genetics of this malignancy are often different from the ones of cutaneous melanomas, with a rare v-raf murine sarcoma viral oncogene homolog B1 (BRAF) positivity and an increased presence of v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (c-KIT) and neuroblastoma rat sarcoma (RAS) viral oncogene homolog (NRAS) mutations. This evidence concerns the gene BRAF and cutaneous melanoma.