In healthy mouse liver, Gremlin-1 expression was undetectable, but others have previously found increased mRNA expression in murine fibrotic liver in Mdr2-/- mice fed a cholate-containing diet (Boers et al., 2006) and porcine serum-induced murine liver fibrosis (Zhang et al., 2017). Here, ABCB4 is linked to Hepatic fibrosis.