CD8A and neoplasm: By breaking down glycerolysin, these bacteria promote the activation of CD8(+) T cells, thereby enhancing immune surveillance and inhibiting the growth of colon tumors (Zhang et al., 2023); Fusobacterium nucleatum and Peptostreptococcus anaerobius were more common in tumor tissues, among them, Fusobacterium nucleatum plays a multifaceted role in colorectal cancer progression.