Gene GRB7, which encodes 535 amino acids, is located on chromosome 17q12 along with ErbB2. It initially garnered attention due to its frequent co-amplification with ErbB2 in various human cancers (Selbach et al., 2009; Meric-Bernstam et al., 2019; Varis et al., 2002; Lim et al., 2014). Here, GRB7 is linked to cancer.