PDHB and brain ischemia: Ten genes (FDX1, LIPT1, LIAS, DLD, MTF1, DLAT, PDHA1, PDHB, GLS, and CDKN2A) associated with cuproptosis were intersected with genes related to brain ischemia, revealing that all 10 genes were brain ischemia-related genes (refer to Figure 2).