LEPR and chronic kidney disease: Next, we searched the Kidney Interactive Transcriptomics database (Table 1), particularly focusing on data from a recent scRNA-seq study of a multifactorial CKD model in female mice in comparison with female wild-type control mice — the CKD model (AAV mice) was characterized by obesity and diabetes caused by a homozygous point mutation in the gene for the leptin receptor (db/db), hypertension induced by adeno-associated virus mediated renin transgene combined with unilateral nephrectomy [10].