A previous study demonstrated that treating cerebral infarction mice model with FGFC1 (10 mg/kg) reduced the formation of hemorrhage and inflammation compared to t-PA treatment (10 mg/kg), which was due to decreasing the production of IL-1β, TNF-α, and IL-6 mRNA with the treatment of FGFC1 at 3 h after ischemia (Shibata et al., 2010). The gene discussed is PLAT; the disease is cerebral infarction.