Similarly, we observed seizure control in specific GESs, including Dravet syndrome (mainly caused by SCN1A mutations) and LGS, which can involve mutations in CDKL5, DNM1, STXBP1, or SCN2A genes. The gene discussed is SCN2A; the disease is encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.