AF detection rates were 13.9%/year, 11.6%/year, 39.9%/year, and 65.1%/year in patients with BNP levels ≤18.1, >18.1 to ≤43.4, >43.4 to ≤100.0, and >100 pg/mL, respectively (log-rank trend p < 0.01) (Supplementary Figure S1). The gene discussed is NPPB; the disease is atrial fibrillation.