Compared to survivors, non-survivors of sepsis had significantly lower proportions and absolute counts of Tr B cells, significantly lower proportions of CD5+ B cells, and significantly higher proportions of DN B cells on day 1 (Table 2), with the difference in absolute CD5+ B cells count almost reaching statistical significance (2.10 [0.84–13.84] vs. 5.06 [2.48–13.71], P = 0.071). Here, CD5 is linked to Sepsis.