Our study found that, residual tumor cells in CRLM undergo lipid metabolic adaptation after iRFA, which leads to increased infiltration of CD177hiPAD4hi neutrophils, mediated by CXCL5‐CXCR1/2, and the release of NETs to promote tumor metastasis (unpublished data). The gene discussed is CXCL5; the disease is neoplasm.