HMGCS1 and metabolic dysfunction-associated steatotic liver disease: The diagnostic accuracy of MVK, HMGCS1, TM7SF2, and FDPS for NAFLD was confirmed by ROC analysis, as the AUC values for FDPS, MVK, and TM7SF2 genes exceeded 0.7 in the datasets GSE135251 and GSE126848 datasets (Figures 5A,B).