IL18 and cancer: One mutant allele in IL-18 C-607A polymorphism increased the chance of cancer (OR = 5.359, 95% CI = 2.95–9.70, P < 0.001) and two mutant alleles increased more (OR = 7.083, 95% CI = 2.61–19.15, P < 0.001) (Table 2).