OTUB2 and colitis: Irradiated Otub2+/+ mice receiving Otub2–/– bone marrow (KO → WT) were more sensitive to DSS‐induced experimental colitis than irradiated Otub2+/+ mice reconstituted with Otub2+/+ bone marrow (WT → WT), as shown by the increased body weight loss and disease activity in KO → WT mice (Figure 3C and D).