The GEPIA61 analysis of TCGA62 also showed that the NRF2 mRNA expression level did not show any statistically significant disparity between tumour and normal tissues (Figure S5C), which means that the regulation of NRF2 may primarily occur through the PTM, which modulate protein stability of NRF2 and subsequently impact its function. The gene discussed is NFE2L2; the disease is neoplasm.