Small-vessel vasculitis driven by deposits of IgA-C3 ICs [48], or IgA vasculitis, formerly known as Henoch–Schönlein purpura (HSP), has also been reported in children with COVID-19, suggesting that SARS-CoV-2 infection may be a trigger [49]. This evidence concerns the gene C3 and Henoch-Schoenlein purpura.