Consistent with the above observations in GC cell lines, PDCs with high copy numbers of TEAD4 (#1, #2) were clearly more sensitive to GLUP than were PDCs with low copy numbers of TEAD4 (#3, #4) (Fig. 8E), again indicating the dependence of the GLUP therapeutic effect on TEAD4 expression of the tumor cell. Here, TEAD4 is linked to neoplasm.