In BD versus progressors, 78 over-represented pathways were identified (p< 0.05; S15 Table in S1 Data), involving ALK and cytokine signaling (MSN, GRB2, HSPA9, NFKBIA, SP100, MSN, HLA-DRA, GZMB, GRB2, JUNB) and RNA metabolism (NCBP2, SF3B1, SRSF11, SF1). This evidence concerns the gene GRB2 and Behcet disease.