To investigate whether HIV infection also affects CD8 T cells specific for other antigens, the gene expression profile of CMV-specific CD8 T cells was analyzed in the same HIV-infected individuals (progressors (n = 7), B*57 LTNP (n = 3), non-B*57 LTNP (n = 6), MAVS -/- (n = 7)). The gene discussed is CD8A; the disease is HIV infectious disease.