There are also rare autosomal recessive variants (autosomal recessive hypercholesterolemia), which cause bi-allelic loss-of-function in LDLRAP-1 and a similar phenotype to that of FH, prompting some to refer to this group of disorders as “phenotypic homozygous familial hypercholesterolemia” [14]. The gene discussed is LDLRAP1; the disease is familial hyperaldosteronism.