Zhang et al. found that YAP1 alleviated sepsis-induced acute lung injury by inhibiting ferritin autophagy-mediated ferroptosis; Wu et al. found that the interaction between STING and NCOA4 intensifies the lethality of sepsis by modulating ferroptosis in macrophages as well as the proinflammatory effect (39). This evidence concerns the gene NCOA4 and Sepsis.