In the non-CKD group, VCAM-1 showed a significant positive correlation with age (rho = 0.205, P < 0.001), UACR (rho = 0.141, P = 0.005), and alanine aminotransferase (rho = 0.116, P = 0.021) and an inverse correlation with eGFR (rho = -0.192, P < 0.001), total cholesterol (rho = -0.139, P = 0.006), and LDL cholesterol (rho = -0.137, P = 0.007). Here, VCAM1 is linked to chronic kidney disease.