GPT and Hepatic fibrosis: A recent study involving 261 NASH patients showed thatchanges in NFS, APRI, FIB-4, and aspartate transaminase/alanine aminotransferase (AST/ALT) ratio yielded low diagnostic accuracyfor changes in liver fibrosis after 1 year of lifestyle intervention, whereas asimple panel consisting of glycosylated hemoglobin (HbA1c), platelet, and ALT normalization discriminatedpatients with fibrosis improvement better than the former [87].