The recently discovered tLyp-1 peptide is a ligand that selectively targets neuropilin1 and 2 (NRP1 and NRP2) (Larue et al., 2023), both of which show elevated expression in several tumor types, including non-small cell lung cancer (NSCLC) (Bai et al., 2020). Here, NRP1 is linked to non-small cell lung carcinoma.