Based on different aPL clinical phenotypes, the number of patients with strongly positive EC4d and PC4d were proportionally higher (14% and 36%) in those with MAPS/TP/HA, compared to those with TAPS (0 and 18%) or no APS (0 and 29%) (additionally higher mean EC4d and PC4d levels were observed in the former group) (Table 2). The gene discussed is FASLG; the disease is autoimmune polyendocrinopathy.