in TCeD patients with persistent diarrhea compared to TCeD patients with other persistent symptoms (48); reduced abundance of Actinobacteria in TCeD patients with negative anti-TG2 IgA serology (50); a tendency to lower abundance of Actinobacteria, mainly Bifidobacterium, in the FODMAP diet group compared to controls (52); and lower abundance of Actinobacteria in CeD patients with poly-autoimmunity such as autoimmune thyroiditis (45). The gene discussed is TGM2; the disease is autoimmune thyroid disease.