Cytokines produced during this process, such as interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and interleukin-8 (IL-8), along with chemokines like CCL2 and CCL12, are thought to be pivotal in bridging the progression to prostate cancer. The gene discussed is CXCL8; the disease is prostate carcinoma.