Recent findings by Liu et al.49demonstrated the formation of disulphide bonds within the actin cytoskeleton of SLC7A11‐high cancer cells during glucose starvation, resulting in F‐actin contraction and detachment from the plasma membrane, as well as collapse of the actin cytoskeleton, ultimately leading to cell death known as disulphidptosis (Figure 2).136, 137, 138, 139. This evidence concerns the gene SLC7A11 and cancer.