Before PSM, the univariate analysis revealed that age, sex, AFP, AJCC stage, T stage, tumor recurrence and treatment type were significantly associated with OS and the multivariate analysis revealed that age, sex, AFP, AJCC stage, T stage, tumor recurrence and treatment type were independent prognostic factors of OS (all P < 0.05, Supplementary Table S1). This evidence concerns the gene AFP and neoplasm.