One study found that CD2AP interacted with TKS4 to form a scaffolding protein complex involving in tumor development via regulating the epithelial–mesenchymal transition process in colon cancer [10], whereas another study showed that CD2AP could inhibit gastric cancer metastasis by promoting cellular adhesion and cytoskeleton assembly [14]. The gene discussed is SH3PXD2B; the disease is neoplasm.