IFNα2A has been used in monotherapy or in combination therapy with other drugs to treat viral infections, including chronic hepatitis B and chronic hepatitis C, in addition to different kinds of cancer (including melanoma, renal cell carcinoma, leukemia, melanoma, AIDS-related Kaposi’s sarcoma), HIV, SIV, and LCMV [15,43–50]. This evidence concerns the gene IFNA2 and melanoma.